boron containing assessment

Boron and its compounds: current biological research activities

Here, the discovery of a boron-containing bacterial signal molecule, autoinducer AI-2, a furanosyl-borate diester, was decisive. AI-2 is produced by several bacteria, and the gene encoding its synthesis is widely conserved. ... Murray FJ (1995) A human health risk assessment of boron (boric acid and borax) in drinking water. Regul …

(PDF) Life Cycle Assessment of Boron Industry from

The use of life cycle assessment (LCA) as a tool to guide catalyst development is demonstrated by comparing the environmental impact of acrylic acid production from propylene, the current ...

Full article: Assessment of consumer exposure to boron in …

Based on usage data, consumer products have been estimated to contribute a geometric mean daily intake of 0.1 mg to total boron exposure (WHO 1998) up to as much as 0.47 mg/day (EVM 2003 ). Even at the high end, this is a small fraction (<10%) of the acceptable mean intakes of boron for adults (1–13 mg/day; WHO 1996 ).

Toxicity of boric acid, borax and other boron containing

3 Division for Risk Assessment and Nutrition, Group for Chemical Risk Assessment and GMO, National Food Institute, Technical University of Denmark, Denmark. Electronic address: [email protected]. ... the overall picture indicates that boron-containing compounds are not genotoxic. There was no evidence of the carcinogenicity of boric acid …

Assessment of boron-containing compounds and

Boron-containing compounds and oleoylethanolamide capsules will be synthesized at Nutrition Research Center of Tabriz University of Medical Sciences. ... This clinical trial has been registered by the title of "Assessment of boron-containing compounds and oleoylethanolamide supplementation on the recovery trend in Patients …

Risk Management Scope

Fourteen boron-containing substances were identified as priorities for assessment, given that they met the categorization criteria under section 73 of CEPA. Subsequently, boron-containing substances that may transform into boric acid (i.e. boric acid precursors), with the exception of polymers, were included for assessment efficiency.

Radiologic assessment of a self-shield with boron-containing …

Radiologic assessment of a self-shield with boron-containing water for a compact medical cyclotron. ... The boron-containing water analyzed in the present study was from tank 3, which was near the target. Gamma-ray spectra of a 100 cm 3 sample were obtained with use of a high-purity germanium semiconductor detector ...

A human health risk assessment of boron (boric acid and …

A human health risk assessment was conducted to derive an appropriate safe exposure level in drinking water of inorganic boron-containing compounds (boric acid and borax). Several regulatory agencies have set or plan to set drinking water guidelines or standards for boron (B). Recent publication of reproductive and developmental toxicity ...

The Advancement of Neutron Shielding Materials for the

Recently, boron-containing polymer as a new neutron shielding resin with the heatproof resistance of 300°C has been studied . With the increase of boron areal density, neutron shielding performance can be enhanced with the improvement of the collision between thermal neutrons and neutron shielding polymers . (1) B 4 C or …

Sustainability | Free Full-Text | Life Cycle Assessment of Boron …

Although there are a lot of studies in literature related to the life cycle assessment (LCA) of mining, there are only a few studies done on the boron mining industry. This paper presents an LCA of the boron mining industry including the extraction, beneficiation, and refinement processes. The main purpose is to identify and compare the …

An assessment of the genetic toxicology of novel …

An assessment of the genetic toxicology of novel boron‐containing therapeutic agents - Ciaravino - 2013 - Environmental and Molecular Mutagenesis - …

Boron Neutron Capture Therapy: Current Status …

Boron neutron capture therapy (BNCT) is a re-emerging therapy with the ability to selectively kill tumor cells. After the boron delivery agents enter the tumor tissue and enrich the tumor cells, the thermal …

Boron

Boron in foods and beverages isn't harmful. But boron can cause harm if a person accidentally swallows cleaning products or pesticides that contain certain forms of boron, such as borax (sodium borate) or boric acid. The symptoms of too much boron include nausea, vomiting, diarrhea, rashes, headaches, and convulsions.

Structural and biological assessment of boron doped …

In this work the sol-gel synthesis of bioactive glass nanoparticles containing both boron and copper oxides is reported for the first time in the literature. Two acid/base co-catalysed methods were compared. ... Assessment of the Effect on Cell Proliferation and Expression. Journal of Endodontics, Volume 43, Issue 5, 2017, pp. 751-759.

Boron delivery agents for neutron capture therapy of cancer

These include boron-containing porphyrins, amino acids, polyamines, nucleosides, peptides, monoclonal antibodies, liposomes, nanoparticles of various types, boron cluster compounds and co-polymers. ... Assessment of the results from the phase I/II boron neutron capture therapy trials at the Brookhaven National Laboratory from a …

Current data regarding the structure-toxicity relationship of boron …

There is a boom on the design and use of new boron containing drugs. • Analysis of toxicological data help us to establish structure-toxicity relationship. • Biological activity of boron-containing compounds is related to chemical structure. • It is feasible to design new compounds for medicine by knowledge of boron-toxicity.

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(WHO) established a tolerable daily intake (TDI) for boron of 0.17 mg boron/kg/day that was rounded to 0.2 mg boron/kg/day (or 12 mg boron per day for a 60-kg individual).2 As described later, U.S. government agencies have also conducted risk assessment for boron-containing boric acid using two additional approaches. If the Fresenius product

Draft Screening Assessment

Boron-containing substances that are precursors of boric acid under environmentally and physiologically relevant conditions and concentrations are toxicologically equivalent to boric acid. ... and Austria (2008a) for the risk assessment of boron compounds. Borates have been demonstrated as being able to penetrate damaged or abraded skin (Draize ...

Nanostructured boron agents for boron neutron capture …

Boron neutron capture therapy (BNCT) is a potential radiation therapy modality for cancer, and tumor-targeted stable boron-10 ( 10 B) delivery agents are an important component of BNCT. Currently, two low-molecular-weight boron-containing compounds, sodium mercaptoundecahydro- closo -dodecaborate (BSH) and …

An assessment of the genetic toxicology of novel boron-containing …

Boron-containing compounds are being studied as potential therapeutic agents. As part of the safety assessment of these therapeutic agents, a battery of genetic toxicology studies was conducted. The battery included a bacterial reverse mutation (Ames) assay, an in vitro chromosome aberration assay in peripheral human lymphocytes, and an in vivo ...

A Review of Boron Neutron Capture Therapy: Its History and …

The range of tumoricidal radiation is limited within boron-containing cells. ... Yoshino K, Hatazawa J, Ido T, Honda C, Ichihashi M, Mishima Y. A unique in vivo assessment of 4-[10B]borono-L-phenylalanine in tumour tissues for boron neutron capture therapy of malignant melanomas using positron emission tomography and 4-borono-2 …

Life cycle environmental impact assessment of borax and …

Limited work has been conducted on the life cycle environment impact assessment of boron-containing products as researchers have been more concerned with the environmental risk of boron in boron-containing products and environmental media (Jensen, 2009, Graan et al., 1997, Batayneh, 2012, Edwards et al., 2012) and its toxicity …

The importance of boron in biological systems

An assessment of boric acid and borax using the IEHR evaluative process for assessing human developmental and reproductive toxicity of agents. Reprod. Toxicol. ... Profile of three boron-containing compounds on the body weight, metabolism and inflammatory markers of diabetic rats. Journal of Trace Elements in Medicine and …

Boron delivery agents for neutron capture therapy of cancer

Boron neutron capture therapy is based on the nuclear capture and fission reactions that occur when non-radioactive boron-10, a constituent of natural elemental boron, 80% of which is in the isotopic form of 11 B and 20% as 10 B, is irradiated with low-energy (0.025 eV) thermal neutrons or, alternatively, higher-energy (10,000 eV) …

Radiologic assessment of a self-shield with boron-containing water for

The cyclotron at our hospital has a self-shield of boron-containing water. The amount of induced radioactivity in the boron-containing water shield of a compact medical cyclotron has not yet been reported. In this study, we measured the photon and neutron dose rates outside the self-shield during cyclotron operation. We estimated the …

Boron neutron capture therapy: History and recent advances

Different boron-containing compounds could call for various approaches. For example, because the absorption of nucleosides containing boron is cell cycle dependent, continual delivery may be necessary. ... M. F. Hawthorne and M. W. Lee, 'A critical assessment of boron target compounds for boron neutron capture therapy', …

Full article: Assessment of consumer exposure to …

Most studies of dietary boron intake show a range of 1–2 mg/day. Consumer products have been estimated to contribute a geometric mean daily intake of 0.1 mg to total boron …

Boric Acid, its salts and precursors substance grouping

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Draft Screening Assessment

WebBoron overview for health professionals. Research health effects, dosing, sources, deficiency symptoms, side effects, and interactions here.

Boron neutron capture therapy: History and recent advances

Generation of boron containing agents. More effective and selective boron delivery agents are constantly being developed. The ability of a therapeutic dose of boron-containing material to be selectively absorbed by cancer cells is important to the binary radio-therapeutic technique's success. ... 'A critical assessment of boron target ...

Boron contamination and its risk management in

Boron (B) is released to terrestrial and aquatic environments through both natural and anthropogenic sources. This review describes the current knowledge on B contamination in soil and aquatic environments in relation to its geogenic and anthropogenic sources, biogeochemistry, environmental and human health impacts, remediation …