Selenium in biology
As unique prosthetic group of a variety of enzymes, presumably as Se (2-), Se functions with tocopherol to protect cell and organelle membranes from oxidative damage, to …Web
Role of Selenium in Plants, Animals, and Humans | Biology
Abstract We present a literature review of the significance of selenium in plants, animals, and humans. The selenium concentrations in soils with different compositions and from different regions in Russia are reported. The issue of the selenium content of plants, the main source of this element for humans, is considered. The …Web
Selenium In Biology
Selenium is a component of the amino acids selenocysteine and selenomethionine. In humans, selenium is a trace element nutrient that functions as a cofactor for glutathione peroxidase and certain forms of thioredoxin reductase. Selenium-containing proteins are produced from inorganic selenium via selenophosphate (PSeO33-).Web
Selenium in the Environment, Metabolism and Involvement in …
Selenium is an essential component of selenoproteins playing an important role in many biological functions, such as antioxidant defense, formation of thyroid …Web
Selenium, Selenoproteins, and Immunity
Abstract. Selenium is an essential micronutrient that plays a crucial role in development and a wide variety of physiological processes including effect immune responses. The immune system relies on adequate dietary selenium intake and this nutrient exerts its biological effects mostly through its incorporation into selenoproteins.Web
Biological Activity of Selenium and Its Impact on Human Health
Selenium (Se) is a naturally occurring metalloid element essential to human and animal health in trace amounts but it is harmful in excess. Se plays a substantial role …Web
Selenium Metabolism and Biosynthesis of Selenoproteins in
Abstract As an essential trace element, selenium (Se) plays a tremendous role in the functioning of the human organism being used for the biosynthesis of selenoproteins (proteins containing one or several selenocysteine residues). The functions of human selenoproteins in vivo are extremely diverse. Many selenoproteins have an …Web
Relation between Selenium and Fertility: A Systematic …
Introduction. Selenium (Se) is an important micronutrient for several vital functions, such as deoxyribonucleic acid (DNA) synthesis and modulation of the thyroid metabolism, 1 in addition to promoting the regulation of antioxidant levels in the organism through its action in the glutathione peroxidase (GPx) active center. 2 This mineral is …Web
Current Knowledge on the Importance of Selenium in Food for …
Selenium participates in the protection of cells against excess H2O2, in heavy metal detoxification, and regulation of the immune and reproductive systems as well. ... biology). Selol is a semi-synthetic compound containing selenite. It is a mixture of selenitetriglycerides obtained by incorporating selenic acid (IV) into molecules of fatty ...Web
The Role of Selenium in Pathologies: An Updated Review
Selenium—and more specifically the amino acid selenocysteine—is present in at least 25 human selenoproteins involved in a wide variety of essential biological …Web
Selenium as an Essential Micronutrient: Roles in Cell Cycle and
Selenium is a potent effector of cell growth with a relatively narrow window of tolerance. In the form of selenite, SeMet or SeCys, it functions as an essential micronutrient at levels of ~ 0.1-0.2 μg/g in the diets of experimental animals and livestock, but it becomes a toxic at levels exceeding 5 μg/g [ 31 ].Web
12th International Symposium on Selenium in Biology and …
Hilton Hawaiian Village. February 16-20, 2022. Aloha! It is with great delight that we welcome you all to the 12 th International Symposium on Selenium in Biology and Medicine. This meeting is being held in beautiful Honolulu, Hawaii, U.S.A. Attendees of this meeting will be able to share and learn of cutting edge research being conducted in the …Web
Biological Chemistry of Hydrogen Selenide
2. Chemistry of Sulfur vs. Selenium. Sulfur is approximately 10 5 times more abundant in the human body than selenium, but the latter element is selected for certain biological functions [].It is particularly remarkable that this is achieved, as there are no other two main-group elements that exhibit more similar physical and chemical properties []. ...Web
Selenium in biology: facts and medical perspectives
Selenium in biology: facts and medical perspectives. Several decades after the discovery of selenium as an essential trace element in vertebrates approximately 20 eukaryotic …Web
Selenocysteine Biosynthesis, Selenoproteins, and …
Development of bioinformatics tools led to the identification of entire sets of selenoproteins in organisms, selenoproteomes, which in turn helped explain biological and biomedical effects of dietary selenium and identify new functions of selenium in biology. Roles of selenium and selenoproteins in health have also been addressed through ...Web
Molecules | Free Full-Text | Selenium in Peptide Chemistry
These unique properties of selenium-containing peptides have found numerous applications in the field of chemical biology. For instance, selenium-containing peptides have been used in native chemical ligation (NCL). In addition, the reactivity of Sec can be harnessed to create cyclic and stapled peptides. Other chemical modifications, …Web
The role of selenium in type-2 diabetes mellitus and its metabolic
The red arrow on the Y axis shows hypoglycemia, i.e. ln (Glucose < 2.8 mM) = 1.03, in this random sample of subjects in the Se-deficient region. The green line represents the locally estimated scatterplot smoothing curve (α = 50%) of the combined regions (amended figure published with permission from Redox Biology) [52]. (For interpretation …Web
Beneficial role of selenium in plants | PPT
Environment. Selenium (Se) is a widely studied trace element in human and animal due to its role in antioxidant defense system which is needed for the maintenance of health and hormone balance. During last two decades the beneficial role of Se in plants has been explored by researchers. abunaim3659.Web
The role of selenium metabolism and selenoproteins in cartilage
The role of selenium metabolism and selenoproteins in cartilage homeostasis and arthropathies Introduction. Selenium (Se) is an essential trace element in humans 1, 2. Selenium is generally taken up from the diet... Overview of the selenium …Web
The Role of Selenium in Pathologies: An Updated …
The Role of Selenium in Pathologies: An Updated Review 1. Introduction. Selenium effects on human health are mainly related to the biological role of selenoproteins, even... 2. Cancer. A great interest …Web
Selenium
Main article: Selenium in biology. A number of correlative epidemiological studies have implicated selenium deficiency (measured by blood levels) in a number of serious or chronic diseases, such as cancer, [121] [122] diabetes, [121] HIV/AIDS, [123] and tuberculosis. In addition, selenium supplementation has been found to be a …Web
Microbial selenium metabolism: a brief history, biogeochemistry …
The year 1973 proved to be a banner year for research on the role of selenium in biology, as multiple independent lines of inquiry identified specific biochemical functions for selenium assimilation in both mammals and bacteria. The mammalian enzyme glutathione peroxidase, ...Web
Advances in Research on the Involvement of Selenium in
Selenium is an essential trace element which plays an important role in human immune regulation and disease prevention. Plants absorb inorganic selenium (selenite or selenate) from the soil and convert it into various organic selenides (such as seleno amino acids, selenoproteins, and volatile selenides) via the sulfur metabolic …Web
Selenium-Based Drug Development for Antioxidant and …
Selenium is one of the eight necessary trace elements humans require for active health balance. It contributes in several ways to the proper functioning of selenoprotein. Selenium has received enormous interest recently due to its therapeutic potential against a number of ailments. To date, numerous chemical compounds …Web
Selenium: Its Molecular Biology and Role in Human Health
In the current edition, Selenium: Its Molecular Biology and Role in Human Health expands extensively on the previous editions providing readers with the most significant advances in the rapidly developing selenium field. Evidence from epidemiology and veterinary science supports the essential role of selenium in (human) health, but its split personality in both …Web
Chapter 15. Selenium
The role of selenium in human metabolic processes. Our understanding of the significance of selenium in the nutrition of human subjects has grown rapidly during the past 20 years (1, 2).Demonstrations of its essentiality to rats and farm animals were followed by appreciation that the development of selenium-responsive diseases often reflected the distribution of …Web
Understanding the Redox Biology of Selenium in the Search of
Selenium (Se) is an essential trace nutrient required for optimal human health. It has long been suggested that selenium has anti-cancer properties. However, clinical trials have shown inconclusive results on the potential of Se to prevent cancer. The suggested role of Se in the prevention of cancer is centered around its role as an …Web
Selenium: Health benefits, sources, and potential risks
Selenium is a mineral that supports cognition, immune system function, and fertility. Most adults need around 55 micrograms (mcg) per day. Sources include nuts, eggs, and some fish. Selenium is a ...Web
Selenium Species in Plant Life
Selenium (Se) is a trace element requisite for plants, animals, humans, and microorganisms (some). Though it is responsible for countless beneficial effects in numerous plant species. But its essentiality for several plants is still debatable and demands in-depth understandings. Inorganic (selenite and selenate) and organic (selenocysteine and ...Web
Selenium: its role as antioxidant in human health
Selenium (Se) is an essential trace element, and its low status in humans has been linked to increased risk of various diseases, such as cancer and heart disease. …Web
